Which browser are you using? Is it the same across different browsers?
Have you checked your project for memory leaks? If you do something like create an object every tick, without ever destroying them - intentionally or unintentionally - your project will consume RAM endlessly.
You should try to reproduce the problem in a minimal new project then we can help more. This is standard procedure for possible bugs anyway since it guarantees the rest of the project is not causing the problem.
A possible workaround if it really is a browser bug is to navigate to a different page, which then waits a second or two and redirects back again. Alternatively instead of reloading the whole page, just reset global variables and jump back to the first layout.