Are you sure you have the very latest drivers?
This kind of thing sounds like nVidia's fault to me. I can't think of anything Construct 2 does that would be broken by another app. It's just an ordinary OpenGL application. IMO you should report this to nVidia, I don't know what we could change in Construct 2 to stop other apps breaking it, it's probably better to fix those apps!
I bet this system monitor thing is designed for games and somehow breaks apps. Graphics card makers always have rubbish unstable drivers that never work, it's pretty annoying.