Oh yeah, HTML5 is extremely fast on Safari, without needing a bloated wrapper as well so app-size is whatever your game is. It's a nice situation for iOS definitely.
Android 5+ gets this performance improvement as well as not needing a wrapper since its on more recent system webview Chromium. It's ~25% of the Android market now. In a sense, publishing to Android 5+ is a good idea since it limits old crap generic devices crashing on your games and users leaving a 1 star review "crashed". I'm biased against Android though, I just don't see it as a platform that's friendly for small time indies breaking through. iOS and Steam for example, show newly released games based on date. Android doesn't, it only has "Top New" lists which requires marketing grunt to get onto, else nobody will find your app.
So currently the big wrapper is only needed on mobiles with older Android versions & PC, which isn't that big a deal.
With NW improved on memory management and working vsync, C2 is good even for bigger games. I just hope the situation remains good and improves. We do not want major chromium bugs to neuter C2 for months on end ever again. That's the biggest risk with C2, hoping that Google doesn't accidentally break your games.