Try the new profiler in r142 - it should help identify what is causing the long pauses. Note there was a bug in r141 which could cause poor performance in Chrome, so you should upgrade to r142 anyway if you're using that.
The object count's effect on performance depends entirely on what exactly you're doing. The best thing to do is keep an eye on things with the new profiler and see if anything's turning in to a CPU hog.
Sound is probably processed in parallel in a separate core, so is unlikely to affect the framerate.