I think it all comes down to what you want to do. Currently If you want to make games as a hobby/small money/prototyping, then C2 is a good tool for that, but if you want to develop for the mobile devices and for real money then Game Maker Studio looks like a good deal for that.
Having native export to Android and iOS is a big thing and $298 is not much for that.
AppMobi costs $100 per year and is limited to 5 apps/year.
I like Construct2 and I believe it has a chance to become standard software for HTML5 along with something like Spaceport.
I do have faith for CocoonJS and I really hope it works. I currently don't have a wireless connection, so I can't test their launcher.