While I personally find it sensible to use engines that are specifically made for point & click adventures (such as Visionaire Studio, for example), I have made a few point & click things myself in Construct2, mostly educational games.
The reasons why I chose Construct2 for those products over Visionaire (even though we own licenses for the latter, too):
- The licensing model, and specifically the licensing of mobile outputs is very convenient
- You always have the option to publish a web ready version that runs in a browser without any plugins, if a client should request it (happened to us, *after* the project was done, so if we had made it in visionaire, we would have had to reimplement the whole thing for HTML5)
- far superior handling of mobile specific problems, like touch input
You will have a large initial chunk of work to get done, to implement a lot of convenient functionality required by point & click style games, like inventory, dialogue systems, some sort of a state machine, but C2 is able to do that.. it's just not available out of the box, you need to build it up from smaller pieces.