Seems like the problem is related to the graphic card used when launching Construct 2
I'm using for work a laptop with switchable graphic card
I dont know why but a recent W10 update messed with the switch functionnality of the graphic card and it was only using the "intel HD 3000" and not the Radeon
I reinstalled the drivers and set the Radeon as default graphic card and now it's working.
If I switch to the intel HD, I have this error when opening a layout