In terms of CPU usage, is myArray.At(400,400,2) = myArray.At(1,1,2)

Say I had an array with the size (500, 500, 2); 500,000 cells total. In terms of CPU usage, does referencing larger index numbers take longer than smaller index numbers?

For example, in terms of CPU usage, is myArray.At(400,400,2) = myArray.At(1,1,2)

Array lookup has constant time complexity, so it should be the same speed regarless of size and index position.