What's the best way to apporch a mega-man palette swap?

If you played the games, you know what I mean. When Mega Man swaps weapons, his palette changes.

I asked this several years ago, but it appears to be buried. So any insight would be greatly apperricated.

The most straightforward solution is to create multiple animations (for example "WalkRed", "WalkBlue", "AttackRed" etc.), or multiple sprites - PlayerRed, PlayerBlue.

Or you can try Replace Color effect.