Yes, you'll find the option in the system conditions.
Let's start with creating 3 global variables names i, j and k.
Add event -> System -> Compare two values -> i * j = k
or you could also do
Add event -> System -> Compare Variable -> i = k/j
Both these should return true as long as i = 2, j = 3 and k = 6.
Or if you want to just take 2 globals and do pure math, try using an Action.
Add action -> System -> Set Value -> k = i * j