Well, I guess you could, be it might but pretty complex and delicate.
For sure, C2's runtime is javascript and not meant by default to execute python.
A quick google search seems to return some python compiled/ers into javascript.
You could first compile your python code and then use the browser object's actions "Execute javascript" nor "ExecJS".
Be sure to read the "Risks with Javascript string execution" of the manual article, and be sure about what you're doing.
Also it's a long stretch, relying on external compilers, hoping they are compatible and compliant with the same JS standards used by C2 and browsers, and then making sure you're executing their code correctly.
Maybe you should detail a bit more what exactly is your intent by using Python.