I have cintiq 12 .The slate is 12 zoll too.
I was in search for a additional mobile scetchbook similar cintiq (with direct eye contact)
...and now, I use the slate more as my desktop PC, and that very comfortable on my sofa *gg* I'm very happy !
I can only speak as an illustrator. I'm not a painter, but for me the drawing feeling is naturally.
The pen is pressure Sensitive, stroke draw is in realtime and you can erase with the back of pen. Summary, it's for me wacom like.
My most used favorite drawing tools on slate are Flash CS5, MangaStudioEx, Illuststudio, sketchbook pro and xara Designer.
My tips If you buy:
-Be sure you have install all new driver(from asus website) .
-It is better uncheck the Finger touch option when you want to draw,
-I have buy this pen only as additional ,but I like it more as the included stylus