When working on big/huge projects (in terms of size of the content) on flash/virtual/online drive, give them the correct amount of time to save before quitting C2/removing your drive from the computer. That kind of errors does come from such an issue where your project actually did not correctly saved.
Also regular storage disks may be subject to failure (electricity issue, deteriorated clusters,...).
Moreover virtual/external disks like that may be subject to even more failure and instability.
If the issue comes from your hardware, no need to come here asking for answers.
It's also not that good practice to use caps locks for the titles of files (and in your posts for that matter).
To retrieve and save your work, do rely on backup options.
If you haven't, too bad for you your "work" might be lost.
As a capx, unzip it somewhere in a temporary folder.
This is now a project folder, so you should still be able to directly open the png file to see if it does contain data.
If it does, you may have to edit the XML file for your project.
I think even with such an error you should still be able to open your project and go into it to check what object is missing the texture and loading it up again.
Then save up that folder as a capx again.