While I do like RPG Maker, and have used it on and off since the PS1 version, it really is only catered to making one specific type of game. Where as C2 is more like a sandbox where you can create anything you want, RPG Maker designed just for making RPGs. There are scripts to create more Zelda-esque titles, different battle systems, or different dialogue options, but some of them aren't the most intuitive and most only work for certain versions of the software.
With C2, you would have to build all the mechanics that come with RPG Maker, so it all depends on how much control you want over your game.
So with that said, if you are interested in making an RPG, I would at least try RPG Maker. It comes with everything you need, but if you want something that truly stands on it's own you would want to create all the art and music yourself, instead of using the prepackaged stuff.
I think VX Ace may still be the most popular version, but MV uses HTML5 so you can export to more devices.. There's always a trial version of the software if you would like to try it out.