I just got Construct 2 yesterday so I'm still finding my way around it, but I've already had a few crashes.
Each time I had a sprite selected and then pressed CTRL+mouse scroll wheel to zoom in to place it, at which point Construct stopped working.
Both times I only had 2 layers and a couple of objects in the project.
I'm running Windows 7 64bit on a Dell 5520 with an Intel Core i5-3210M CPU — and 6GB of RAM.
Each time I had Firefox open with several tabs and I think one of the times I had Photoshop open as well.