DWing and Beerman,
That error is mainly caused by insufficient VRAM. I was able to measure the vram usage on my system with my Intel graphics card driver, and I got these numbers:
8 Mb for normal system use.
43 Mb after opening construct and selecting "New"->"Direct X app".
--"Run Layout" 48 Mb, the runtime reports 0.00 mb vram usage.
45 Mb after adding a 512x512 Sprite.
--"Run Layout" 51 Mb, the runtime reports 1.00 mb vram usage.
63 Mb after adding one or more layer effects.
--"Run Layout" 71 Mb, the runtime reports 6.69 mb vram usage.
So in general if you add 5 Mb to what the runtime says you are using you should get approximately how much vram your game is currently using.
With 64 Mb of vram you can still edit and run your game at the same time if you avoid Effects and Transitions, but you still might run out of vram if you use a lot of graphics. In that case you would have to export your cap, close construct, and run the exported program to test it.