Economic simulators/RPG are hard to do on any engine. It's completely doable on Construct 2, but honestly, I wouldn't recommend it.
You're better off using a "more free" framework... Unity is OK but you need to struggle a bit with 2D (not a mess, just small workarounds). If you know about coding, I'd either grab Unity, Haxe Flixel or something free that can export to anything.
Actually, now that you mentioned it, it's doable on Ren'Py. You can set any number of variables and checks, and customize the UI to be more like an economic sim, and not a dating sim. Check games like Loren The Amazon Princess (I think), they have quite strong RPG/Economic Sim elements. Just replace that anime things with actually useful images for your game.
Mind that Life Quest 2 has tons of "game feel/juicy" settings. I think that isn't doable on Ren'Py. If you want to have that kind of professional quality, research if the engine you're going to use allows easy integration with "tweening" (look it up). Here with construct 2 we have EasyTween. Still, I wouldn't recommend C2 for that. Ren'Py is easier, but it will feel worse.