It is possible, but quite a bit of a roundabout method. Any particular reason you need to use XML?
Here is a rough idea of the steps:
Import your XML file as a project file.
Load the XML file into memory with AJAX.request.
Access the data with AJAX.lastdata.
Use tokenat() to parse the information you need from your XML file.
Use the information you got to set the Sprite Animation, or to destroy and replace with another Sprite.