I have heard of people using C2 for making a web site (and have seen a couple examples), but it is really not suited for that job. There is no way for search engines to index the content - so people will never find you by searching. It is much more complicated to make it responsive (adapt to screen size and orientation). If you want a scroll bar, you have to make your own, loads slower (because of the engine overhead), and other issues.
I use C2 to make apps that are launched from a web site (and interact with a database) - but they are for private use, not available to the general public, so SEO is not a concern.
It is possible to make use of the whole screen (and center things), have a (custom) scroll bar, and make a nice looking interface... just not ideal for a typical web site.