System Specs: win 7, CPU: AMD II X4 630, RAM: 4GB, AMD Radeon HD6900
Opens fine for me. I haven't played your web version, so not sure how it compares, but it seemed to play fine with no discernible bugs through a good part of the first level.
Bear in mind that Awesomium is still in alpha release I believe so they probably still have bugs to iron out. I dunno if their discussion forums track which systems have issues currently?
I do have feedback on gameplay, but I guess it's not what you're after at the moment :)