I keep loosing works when C2 crashes (from time to time, with some kind of resource not available message). Essentially, I am loosing the work between the time a last autosave happens and i manually save the file again.
At the same time I often Run or Debug Layouts to test what i do. Best, if there is an option to have the game saved everything i run or debug the layout. It will take a bit time to save, but then i know that i will not loose any work which is much more frustrating.