The class I was teaching last year participated in the European project iTEC, where we looked at new ways to learn in the future classroom. iTEC is a project by European schoolnet, which is the network of 31 European Ministries of Education.
We participated in both cycle 4 and 5 (there were 5 cycles in total) with games and gamification to learn subjects, and I choosed to use Construct 2 for development. In the final cycle (last year) the students even got to make some demo games, which impressed the researchers.
Here you can read a piece about it (in Norwegian, so use Google translate): https://iktipraksis.iktsenteret.no/blogg/utvikling-av-l%C3%A6ringsspill-ved-nord-gudbrandsdal-vgs
You can also find the games in the bottom of the article, and they are all in english. Keep in mind that this was only done in a short time span of the whole school year.